Effects of microwave exposure and temperature on survival of mice infected with Streptococcus pneumoniae (journal version)

Technical Report · Thu Jan 01 04:00:00 EST 1987

OSTI ID:6596360

Liddle, C G; Putnam, J P; Lewter, O H

Female CD-1 mice were injected with an LD50 dose of Streptococcus pneumoniae and then exposed to 2.45 GHz (CW) microwave radiation at an incident power density of 10 mW/cm2 (SAR approximately equals 6.8 W/kg), 4 h/d for 5 d at ambient temperatures of 19, 22, 25, 28, 31, 34, 37 and 40/sup 0/C. The results showed that survival of sham exposed animals increased as ambient temperature increased until 37/sup 0/C when the thermoregulatory capacity of the animals was exceeded and deaths due to hyperthermia occurred. Survival of microwave exposed animals was significantly greater than the shams (approximately 20%) at each ambient temperature below 34/sup 0/C. An analysis of the data suggests that the hyperthermia from microwaves may be more effective in increasing survival than conventional hyperthermia. The results indicate that microwave radiation may be beneficial to infected animals at low and moderate ambient temperatures, but detrimental when combined with high ambient temperatures.

• Research Organization: Environmental Protection Agency, Research Triangle Park, NC (USA). Health Effects Research Lab.
• OSTI ID: 6596360
• Report Number(s): PB-89-105977/XAB; EPA-600/J-87/424
• Country of Publication: United States
• Language: English

Related Subjects

560400* -- Other Environmental Pollutant Effects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BACTERIA
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY TEMPERATURE
ELECTROMAGNETIC RADIATION
HYPERTHERMIA
LABORATORY ANIMALS
MICROORGANISMS
MICROWAVE RADIATION
RADIATION EFFECTS
RADIATIONS
STREPTOCOCCUS
TEMPERATURE EFFECTS