Human teratoma cell culture system for the prescreening of environmental chemicals that may initiate or promote tumor formation
Conference
·
OSTI ID:6595633
A cell clone, P3, from a human teratocarcinoma cell line was isolated and characterized for use as targets in mutagenesis studies to identify potential carcinogens and elucidate the genetic events most likely to result in malignant transformation. Human breast carcinoma BJ cells were incorporated into the P3 system to supply the necessary enzymes for chemical activation. 51 references, 3 figures, 3 tables. (ACR)
- Research Organization:
- Argonne National Lab., IL (USA)
- DOE Contract Number:
- W-31109-ENG-38
- OSTI ID:
- 6595633
- Report Number(s):
- CONF-8403140-1; ON: DE84015827
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550300 -- Cytology
560301* -- Chemicals Metabolism & Toxicology-- Cells-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
CARCINOGEN SCREENING
CARCINOMAS
CELL CULTURES
DISEASES
MAMMALS
MAN
METABOLIC ACTIVATION
NEOPLASMS
PRIMATES
SCREENING
VERTEBRATES
560301* -- Chemicals Metabolism & Toxicology-- Cells-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
CARCINOGEN SCREENING
CARCINOMAS
CELL CULTURES
DISEASES
MAMMALS
MAN
METABOLIC ACTIVATION
NEOPLASMS
PRIMATES
SCREENING
VERTEBRATES