/sup 99m/Tc diphosphonate imaging in the differential diagnosis of thyroid nodules
Journal Article
·
· Clin. Nucl. Med.; (United States)
Early /sup 99m/Tc diphosphonate (DP) imaging was performed in 122 patients with cold thyroid nodules in an effort to differentiate benign nodules from malignant. Immediately upon completion of the routine 24-hour /sup 123/I uptake and multiview pinhole imaging, /sup 99m/Tc DP was injected intravenously and three serial 3-minute anterior images of the thyroid gland were obtained. Follow-up information was available in 85 patients. All cystic lesions had less /sup 99m/Tc uptake as compared with the uptake in the normal parts of the thyroid. However, 48 of 50 solid nodules had /sup 99m/Tc DP uptake to the same or greater degree than did the normal gland. The other two had mixed pattern on ultrasound examination. Most of the carcinomas (8 of 10) and benign adenomas (15 of 22) had identical appearance on /sup 99m/Tc scans, i.e., uptake in the lesion being the same as in the normal thyroid. It appears that by using this technique it is possible to separate solid nodules from cystic, but not benign from malignant.
- Research Organization:
- Division of Nuclear Medicine, Indiana University School of Medicine, Indianapolis
- OSTI ID:
- 6584086
- Journal Information:
- Clin. Nucl. Med.; (United States), Journal Name: Clin. Nucl. Med.; (United States) Vol. 7:8; ISSN CNMED
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
550901 -- Pathology-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARCINOMAS
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
ENDOCRINE GLANDS
ESTERS
GLANDS
HOURS LIVING RADIOISOTOPES
IMAGES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC PHOSPHORUS COMPOUNDS
ORGANS
PATIENTS
PHOSPHONIC ACID ESTERS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
TECHNETIUM 99
TECHNETIUM ISOTOPES
THYROID
UPTAKE
USES
YEARS LIVING RADIOISOTOPES
550901 -- Pathology-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARCINOMAS
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
ENDOCRINE GLANDS
ESTERS
GLANDS
HOURS LIVING RADIOISOTOPES
IMAGES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC PHOSPHORUS COMPOUNDS
ORGANS
PATIENTS
PHOSPHONIC ACID ESTERS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
TECHNETIUM 99
TECHNETIUM ISOTOPES
THYROID
UPTAKE
USES
YEARS LIVING RADIOISOTOPES