Exocrine pancreatic neoplasms in the mummichog (fundulus heteroclitus) from a creosote-contaminated site

Technical Report · Sat Jan 01 04:00:00 EST 1994

OSTI ID:6579527

Fournie, J W; Vogelbein, W K

A high prevalence of exocrine pancreatic neoplasms occurred in mummichog, Fundulus heteroclitus, from a creosote-contaminated site in the Elizabeth River, Virginia. A total of 20 neoplasms occurred in a group of about 1100 fish evaluated histologically. Of 240 adult fish collected during October 1991, 3.3% had pancreatic neoplasms. Adjusted total lesion prevalence for fish belonging to size classes III and IV was 6.7%. Pancreatic neoplasms were not observed in 234 fish collected at this site during May 1991, nor were pancreatic tumors found in 420 fish examined from 7 other localities. Lesions involved both mesenteric and intrahepatic exocrine pancreas and ranged from well-differentiated acinar cell adenomas to poorly differentiated acinar cell carcinomas.

• Research Organization: Virginia Inst. of Marine Science, Gloucester Point, VA (United States)
• OSTI ID: 6579527
• Report Number(s): PB-95-155180/XAB; CNN: EPA-R-818165-01
• Country of Publication: United States
• Language: English

Related Subjects

54 ENVIRONMENTAL SCIENCES
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AROMATICS
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ENVIRONMENTAL EFFECTS
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ORGANIC COMPOUNDS
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POLYCYCLIC AROMATIC HYDROCARBONS
TOXICITY
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