Exocrine pancreatic neoplasms in the mummichog (fundulus heteroclitus) from a creosote-contaminated site
A high prevalence of exocrine pancreatic neoplasms occurred in mummichog, Fundulus heteroclitus, from a creosote-contaminated site in the Elizabeth River, Virginia. A total of 20 neoplasms occurred in a group of about 1100 fish evaluated histologically. Of 240 adult fish collected during October 1991, 3.3% had pancreatic neoplasms. Adjusted total lesion prevalence for fish belonging to size classes III and IV was 6.7%. Pancreatic neoplasms were not observed in 234 fish collected at this site during May 1991, nor were pancreatic tumors found in 420 fish examined from 7 other localities. Lesions involved both mesenteric and intrahepatic exocrine pancreas and ranged from well-differentiated acinar cell adenomas to poorly differentiated acinar cell carcinomas.
- Research Organization:
- Virginia Inst. of Marine Science, Gloucester Point, VA (United States)
- OSTI ID:
- 6579527
- Report Number(s):
- PB-95-155180/XAB; CNN: EPA-R-818165-01
- Country of Publication:
- United States
- Language:
- English
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