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The frequency, etiology, and significance of septal involvement in acute inferior myocardial infarction

Conference · · J. Nucl. Med.; (United States)
OSTI ID:6572848
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Involvement of the interventricular septum (IVS) in acute myocardial infarction is usually attributable to proximal left anterior descending artery (pLAD) occlusion; however, the IVS is also supplied by the posterior descending branch of the right coronary artery (RCA). Therefore, the authors investigated the frequency and significance of IVS involvement in acute inferior myocardial infarction (IMI) in 34 consecutive patients with IMI using thalium-201 scintigraphy (Tl-201), radionuclide ventriculography (RNV) and coronary angiography. Tl-201 perfusion defects of the IVS were found in 16 pts (Group 1), 11 of whom also had an IVS wall motion (WM) abnormality. In all 18 patients with normal IVS Tl-201 uptake (Group 2), IVS WM was also normal. IMI was due to RCA thrombosis in all 16 (100%) pts in Group 1 but in only 11 (61%) of the pts in Group 2; the remaining 7 had circumflex thrombosis. The frequencies of multiple-vessel disease and pLAD stenosis were similar in Group 1 and in Group 2 (81% vs 78% and 31% vs 33%, respectively). The authors conclude that IVS involvement in acute IMI 1) is frequent (47%), 2) appears to result from RCA thrombosis and cannot be attributed to pLAD disease, and 3) is associated with greater RV dysfunction.

Research Organization:
Cedars-Sinai Med. Ctr., Los Angeles, CA
OSTI ID:
6572848
Report Number(s):
CONF-840619-
Journal Information:
J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 25:5; ISSN JNMEA
Country of Publication:
United States
Language:
English

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Related Subjects

550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
550901 -- Pathology-- Tracer Techniques
551001* -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BIOMEDICAL RADIOGRAPHY
BODY
CARDIOGRAPHY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASE INCIDENCE
DISEASES
DYNAMIC FUNCTION STUDIES
ELECTRON CAPTURE RADIOISOTOPES
ETIOLOGY
HEART
HEAVY NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
MUSCLES
MYOCARDIAL INFARCTION
MYOCARDIUM
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATHOLOGICAL CHANGES
RADIOCARDIOGRAPHY
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOLOGY
RADIONUCLIDE KINETICS
SCINTISCANNING
SECONDS LIVING RADIOISOTOPES
THALLIUM 201
THALLIUM ISOTOPES
UPTAKE