Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

Thyroid and associated polyglandular neoplasms in patients who received head and neck irradiation during childhood

Journal Article · · Head Neck Surg.; (United States)
One hundred fifty-one patients with a history of childhood irradiation to the head, neck, and thorax had neck explorations (142 for cold thyroid nodules and 9 for hypercalcemia). Fifty-nine of the patients had thyroid carcinoma, and associated glandular tumors were found in 20 others. In addition, 6 female patients developed breast carcinoma; 4 of these women also had thyroid carcinoma. In this series, 48.6% of the patients irradiated for acne and 36.4% with tonsil and adenoid irradiation developed thyroid carcinoma, but only 10.5% with thymic irradiation did so. It is suggested that the workup on these patients include not only complete thyroid and parathyroid testing, but also a careful examination of all salivary glands, both major and minor. Women should have thorough breast examinations and should perhaps be followed as if they were in the potentially high-risk breast group. When thyroid surgery is performed, a total thyroidectomy is recommended.
Research Organization:
Division of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA
OSTI ID:
6565634
Journal Information:
Head Neck Surg.; (United States), Journal Name: Head Neck Surg.; (United States) Vol. 1:5; ISSN HNSUD
Country of Publication:
United States
Language:
English

Similar Records

A STUDY OF THYROID CANCER IN CHILDREN
Journal Article · Thu Nov 30 23:00:00 EST 1961 · American Journal of Surgery (U.S.) · OSTI ID:4723997
Thyroid neoplasms after radiation therapy for adolescent acne vulgaris. [X radiation]
Journal Article · Sat Dec 31 23:00:00 EST 1977 · Arch. Dermatol.; (United States) · OSTI ID:5038381
Primary hyperparathyroidism and nonmedullary thyroid cancer
Journal Article · Sun Feb 28 23:00:00 EST 1982 · Am. J. Surg.; (United States) · OSTI ID:5027051

Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
560151 -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
DELAYED RADIATION EFFECTS
DISEASES
ENDOCRINE GLANDS
GLANDS
IRRADIATION
LOCAL IRRADIATION
MAMMARY GLANDS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIATION EFFECTS
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
THERAPY
THYROID