Clinical applications of scanning electron microscopy and X-ray microanalysis in dermatology

Journal Article · Sun Jan 01 04:00:00 EST 1984 · Scanning Electron Microsc.; (United States)

OSTI ID:6546870

Forslind, B

Scanning electron microscopy is frequently applied to dermatological problems, as is evident from a review of the recent literature. In this paper, preparation methods and new techniques allowing experimental studies on the integumentary system are emphasized. Quantitative analysis in the electron microscope by use of energy-dispersive X-ray microanalysis (EDX) has become an important accessory technique. EDX can, for instance, be used to study problems involving physiological changes induced in skin by agents causing contact reactions. Recently, it has been shown that treatment with DNCB, chromate and nickel causes changes in elemental distribution in guinea-pig skin. In addition, elemental uptake in the integumentary system and in pathological inclusions in skin can be analyzed.

• Research Organization: Dept. of Medical Biophysics, Experimental Dermatology Research Group, Karolinska Institutet, Stockholm
• OSTI ID: 6546870
• Journal Information: Scanning Electron Microsc.; (United States), Journal Name: Scanning Electron Microsc.; (United States) Vol. 000084:1; ISSN SEMYB
• Country of Publication: United States
• Language: English

Related Subjects

550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMALS
BODY
CHEMICAL ANALYSIS
CHROMATES
CHROMIUM COMPOUNDS
DATA ANALYSIS
DIAGNOSIS
DISEASES
ELECTRON MICROSCOPY
ELEMENTS
GUINEA PIGS
MAMMALS
METALS
MICROSCOPY
NICKEL
NONDESTRUCTIVE ANALYSIS
ORGANS
OXYGEN COMPOUNDS
PATHOLOGY
PHYSIOLOGY
QUANTITATIVE CHEMICAL ANALYSIS
RODENTS
SCANNING ELECTRON MICROSCOPY
SKIN
SKIN DISEASES
TRANSITION ELEMENT COMPOUNDS
TRANSITION ELEMENTS
UPTAKE
VERTEBRATES
X-RAY EMISSION ANALYSIS