State of spermatogenesis in rats flown aboard Kosmos-690 biosatellite. [Effects of space flight factors on. gamma. radiosensitivity of germ cells in male rats]

Journal Article · Thu Oct 26 00:00:00 EDT 1978 · Space Biol. Med. (USSR) (Engl. Transl.); (United States)

OSTI ID:6528534

Plakhuta-Plakutina, G I

In studying the modifying effects of space flight factors on radiosensitivity of various physiological systems of the body, of definite interest is the reaction of critical organs, in particular the testes, which have a high degree of heterogenic sensitivity of spermatogenic epithelium. Impairment of proliferative activity of testicular epithelium is largely related to the radiovulnerability of cells of the stem type, spermatogonia. In determining the modifying effects of weightlessness and other factors of space flights, it is necessary to compare the cytological state and quantitative evaluation of the incidence of spermatogonia, spermatocytes, spermatids, and spermatozoa in order to determine the possible injury to specific stages of spectrogenesis, depending on the radiation doses during space flights and in ground-based model experiments. The effects of radiation under weightless conditions on the reproductive glands of 30 male Wistar rats flown aboard Kosmos-690 and submitted to prolonged ..gamma.. radiation on the 10th day of the flight were investigated.

• OSTI ID: 6528534
• Journal Information: Space Biol. Med. (USSR) (Engl. Transl.); (United States), Vol. 12:5; Other Information: Translated from Kosm. Biol. Aviakosmicheskaya Med.; 12: No. 5, 26-31(1978)
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
MORPHOLOGICAL CHANGES
RADIOINDUCTION
SPACE FLIGHT
RADIOSENSITIVITY EFFECTS
SPERMATOGENESIS
BIOLOGICAL RADIATION EFFECTS
SPERMATOGONIA
RADIOSENSITIVITY
SPERMATOZOA
TESTES
BIOSATELLITES
CESIUM 137
EXTERNAL IRRADIATION
GAMMA RADIATION
KOSMOS SATELLITES
RATS
WHOLE-BODY IRRADIATION
ALKALI METAL ISOTOPES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BODY
CESIUM ISOTOPES
ELECTROMAGNETIC RADIATION
GAMETES
GAMETOGENESIS
GERM CELLS
GONADS
IONIZING RADIATIONS
IRRADIATION
ISOTOPES
MALE GENITALS
MAMMALS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
RODENTS
SATELLITES
VERTEBRATES
YEARS LIVING RADIOISOTOPES
560152* - Radiation Effects on Animals- Animals