Measurement of left-to-right shunts by gated radionuclide angiography: concise communication

Journal Article · Wed Dec 01 04:00:00 EST 1982 · J. Nucl. Med.; (United States)

OSTI ID:6525416

Rigo, P; Chevigne, M

Gated cardiac blood-pool scans allow comparison of left- and right-ventricular stroke volume. We have applied these measurements to the quantification of left-to-right shunts (QP/QS) in nine patients with atrial septal defects, one patients with partial anomalous pulmonary venous return, four patients with ventricular septal defects, and two patients with patent ductus arteriosus. None of these patients had combined lesions. QP/QS was measured as the right-ventricular (RV) stroke counts divided by the left-ventricular (LV) stroke counts and as the LV stroke counts divided by the RV stroke counts in patients with RV and LV diastolic volume overload respectively. All patients had also QP/QS measurements by oximetry and first-pass radionuclide angiography. The stroke-count measurements indicated the overloaded ventricle in all patients. QP/QS determined by equilibrium gated studies correlated well with those obtained by oximetry (r . 0.79). Reproducibility of the equilibrium measurements was good. We conclude that gated cardiac blood-pool scans can measure left-to-right shunts and can distinguish between shunts with RV and LV volume overload.

• Research Organization: University of Liege, Belgium
• OSTI ID: 6525416
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 23:12; ISSN JNMEA
• Country of Publication: United States
• Language: English

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59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BIOMEDICAL RADIOGRAPHY
BLOOD CIRCULATION
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
DYNAMIC FUNCTION STUDIES
HEART
LABELLED COMPOUNDS
MEDICINE
NUCLEAR MEDICINE
ORGANS
PATHOLOGY
PATIENTS
RADIOLOGY
RADIOPHARMACEUTICALS