Identification of metabolites from the degradation of fluoranthene by Mycobacterium sp. strain PYR-1

Journal Article · Mon Mar 01 04:00:00 EST 1993 · Applied and Environmental Microbiology; (United States)

OSTI ID:6524594

Kelley, I; Freeman, J P; Evans, F E; Cerniglia, C E ^[1]

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1. Food and Drug Administration, Jefferson, AR (United States)

Polycyclic aromatic hydrocarbons (PAHs) such as flouranthene are widespread environmental pollutants shown to be cytotoxic, mutagenic, and carcinogenic. Mycobacterium sp. strain PYR-1 substancially mineralizes fluoranthene in pure culture and in sediments. In this report, additional metabolites of fluoranthene are identified and its possible modes of degradation by Mycobacterium sp. strain PYR-1 are discussed. The experimental results identify metabolites with the intact fluorene configuration and an initial oxygenated metabolite in which the single benzene ring has been attacked. Several metabolic pathways, operating simultaneously, are involved in the degradation of fluoranthen by Mycobacterium sp. strain PYR-1. The low concentrations of metabolites, the rapid evolution of carbon dioxide, and the rapid disappearance of fluoranthene from the medium provide concrete evidence of the usefulness of this Mycobacterium for bioremediation of some PAHs.

• OSTI ID: 6524594
• Journal Information: Applied and Environmental Microbiology; (United States), Journal Name: Applied and Environmental Microbiology; (United States) Vol. 59:3; ISSN AEMIDF; ISSN 0099-2240
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AROMATICS
BACTERIA
BIODEGRADATION
BIOLOGICAL PATHWAYS
CARBON COMPOUNDS
CARBON DIOXIDE
CARBON OXIDES
CARCINOGENS
CHALCOGENIDES
CHEMICAL REACTIONS
CONDENSED AROMATICS
DECOMPOSITION
FLUORENE
HYDROCARBONS
METABOLITES
MICROORGANISMS
MUTAGENS
MYCOBACTERIUM
ORGANIC COMPOUNDS
OXIDES
OXYGEN COMPOUNDS
POLLUTANTS
POLYCYCLIC AROMATIC HYDROCARBONS
SEDIMENTS