Effects of epidermal growth factor on neural crest cells in tissue culture
Journal Article
·
· Exp. Cell Res.; (United States)
Epidermal growth factor (EGF) stimulates the release of hyaluronic acid (HA) and chondroitin sulfate proteoglycan (CSPG) from quail trunk neural crest cultures in a dose-dependent fashion. It also promotes the expression of cell-associated heparan sulfate proteoglycan (HSPG) as detected by immunofluorescence and immunoprecipitation of the /sup 3/H-labeled proteoglycan. Furthermore, EGF stimulates (/sup 3/H)thymidine incorporation into total cell DNA. These results raise the possibility that EGF or an analogous growth factor is involved in regulation of neural crest cell morphogenesis.
- Research Organization:
- Univ. of California, Davis
- OSTI ID:
- 6524195
- Journal Information:
- Exp. Cell Res.; (United States), Journal Name: Exp. Cell Res.; (United States) Vol. 169:2; ISSN ECREA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550301* -- Cytology-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
AMINES
ANIMAL CELLS
ANIMAL TISSUES
AZINES
BETA DECAY RADIOISOTOPES
BIOCHEMISTRY
BIOSYNTHESIS
BODY
CARBOHYDRATES
CELL CULTURES
CHEMISTRY
CHONDROITIN
DAYS LIVING RADIOISOTOPES
DNA
ELECTRON CAPTURE RADIOISOTOPES
EPIDERMIS
EPITHELIUM
FLUORESCENCE
GLUCOPROTEINS
GROWTH
HETEROCYCLIC COMPOUNDS
HYALURONIC ACID
INTERMEDIATE MASS NUCLEI
IODINE 125
IODINE ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LUMINESCENCE
MUCOPOLYSACCHARIDES
NUCLEI
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
OXYGEN COMPOUNDS
PEPTIDES
POLYPEPTIDES
POLYSACCHARIDES
PROTEINS
PYRIMIDINES
RADIOISOTOPES
RIBOSIDES
SACCHARIDES
SKIN
SULFATES
SULFUR COMPOUNDS
SYNTHESIS
THYMIDINE
TISSUES
TRITIUM COMPOUNDS
59 BASIC BIOLOGICAL SCIENCES
AMINES
ANIMAL CELLS
ANIMAL TISSUES
AZINES
BETA DECAY RADIOISOTOPES
BIOCHEMISTRY
BIOSYNTHESIS
BODY
CARBOHYDRATES
CELL CULTURES
CHEMISTRY
CHONDROITIN
DAYS LIVING RADIOISOTOPES
DNA
ELECTRON CAPTURE RADIOISOTOPES
EPIDERMIS
EPITHELIUM
FLUORESCENCE
GLUCOPROTEINS
GROWTH
HETEROCYCLIC COMPOUNDS
HYALURONIC ACID
INTERMEDIATE MASS NUCLEI
IODINE 125
IODINE ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LUMINESCENCE
MUCOPOLYSACCHARIDES
NUCLEI
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
OXYGEN COMPOUNDS
PEPTIDES
POLYPEPTIDES
POLYSACCHARIDES
PROTEINS
PYRIMIDINES
RADIOISOTOPES
RIBOSIDES
SACCHARIDES
SKIN
SULFATES
SULFUR COMPOUNDS
SYNTHESIS
THYMIDINE
TISSUES
TRITIUM COMPOUNDS