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Mechanisms of mutagenesis: analysis through the use of alcohol dehydrogenase in Drosophila. Contract summary, May 1978-October 1980

Technical Report ·
OSTI ID:6522532
The objective was to determine the mechanisms of mutagenesis of several mutagens in Drosophila melanogaster. The effects of mutagenesis on the amino acid sequence of alcohol dehydrogenase (ADH) and the nucleo-1 tide sequence of the ADH gene were studied. Mutations in this gene were generated and the modified nucleotide deduced from the amino acid change ungendered. (ACR)
Research Organization:
Johns Hopkins Univ., Baltimore, MD (USA). Dept. of Biology
DOE Contract Number:
AC02-76EV02965
OSTI ID:
6522532
Report Number(s):
DOE/EV/02965-2; ON: DE83008666
Country of Publication:
United States
Language:
English

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Related Subjects

560301* -- Chemicals Metabolism & Toxicology-- Cells-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINO ACIDS
ANIMALS
ARTHROPODS
BIOLOGICAL EFFECTS
CARBOXYLIC ACIDS
CLONING
DIPTERA
DNA
DROSOPHILA
FLIES
FRUIT FLIES
GENETIC EFFECTS
INSECTS
INVERTEBRATES
MOLECULAR STRUCTURE
MUTAGENESIS
NUCLEIC ACIDS
ORGANIC ACIDS
ORGANIC COMPOUNDS
RESEARCH PROGRAMS