Cerebral glucose metabolic differences in patients with panic disorder
Journal Article
·
· Neuropsychopharmacology; (USA)
OSTI ID:6510724
- NIMH, Bethesda, MD (USA)
Regional glucose metabolic rates were measured in patients with panic disorder during the performance of auditory discrimination. Those regions examined by Reiman and colleagues in their blood flow study of panic disorder were examined with a higher resolution positron emission tomography (PET) scanner and with the tracer (F-18)-2-fluoro-2-deoxyglucose (FDG). In contrast to the blood flow findings of Reiman et al., we did not find global gray metabolic differences between patients with panic disorder and normal controls. Consistent with the findings of Reiman et al., we found hippocampal region asymmetry. We also found metabolic decreases in the left inferior parietal lobule and in the anterior cingulate (trend), as well as an increase in the metabolic rate of the medial orbital frontal cortex (trend) of panic disorder patients. It is unclear whether the continuous performance task (CPT) enhanced or diminished findings that would have been noted in a study performed without task.
- OSTI ID:
- 6510724
- Journal Information:
- Neuropsychopharmacology; (USA), Journal Name: Neuropsychopharmacology; (USA) Vol. 3:4; ISSN NEROE; ISSN 0893-133X
- Country of Publication:
- United States
- Language:
- English
Similar Records
Cerebral blood flow changes during sodium-lactate-induced panic attacks
Intrinsic connections and architectonics of posterior parietal cortex in the rhesus monkey
Measurement of blood-brain hexose transport with dynamic PET: comparison of (/sup 18/F)2-fluoro-2-deoxyglucose and (/sup 11/C)O-methylglucose
Journal Article
·
Thu Mar 31 23:00:00 EST 1988
· Am. J. Psychiatry; (United States)
·
OSTI ID:5237918
Intrinsic connections and architectonics of posterior parietal cortex in the rhesus monkey
Journal Article
·
Sat Jan 09 23:00:00 EST 1982
· J. Comp. Neurol.; (United States)
·
OSTI ID:5464906
Measurement of blood-brain hexose transport with dynamic PET: comparison of (/sup 18/F)2-fluoro-2-deoxyglucose and (/sup 11/C)O-methylglucose
Journal Article
·
Tue Jan 31 23:00:00 EST 1989
· J. Cereb. Blood Flow Metab.; (United States)
·
OSTI ID:6499660
Related Subjects
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ALDEHYDES
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BLOOD FLOW
BODY
BRAIN
CARBOHYDRATES
CENTRAL NERVOUS SYSTEM
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
DISEASES
EMISSION COMPUTED TOMOGRAPHY
FLUORINE 18
FLUORINE ISOTOPES
GLUCOSE
HEXOSES
HOURS LIVING RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIGHT NUCLEI
METABOLISM
MONOSACCHARIDES
NERVOUS SYSTEM
NERVOUS SYSTEM DISEASES
NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
ORGANS
PATIENTS
POSITRON COMPUTED TOMOGRAPHY
RADIOISOTOPES
SACCHARIDES
TOMOGRAPHY
62 RADIOLOGY AND NUCLEAR MEDICINE
ALDEHYDES
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BLOOD FLOW
BODY
BRAIN
CARBOHYDRATES
CENTRAL NERVOUS SYSTEM
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
DISEASES
EMISSION COMPUTED TOMOGRAPHY
FLUORINE 18
FLUORINE ISOTOPES
GLUCOSE
HEXOSES
HOURS LIVING RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIGHT NUCLEI
METABOLISM
MONOSACCHARIDES
NERVOUS SYSTEM
NERVOUS SYSTEM DISEASES
NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
ORGANS
PATIENTS
POSITRON COMPUTED TOMOGRAPHY
RADIOISOTOPES
SACCHARIDES
TOMOGRAPHY