Effect of cimetidine on blood clearance, gastric uptake, and secretion of /sup 99m/Tc-pertechnetate in dogs

Conference · Mon Jun 01 00:00:00 EDT 1981 · Radiology; (United States)

OSTI ID:6502970

Sagar, V V; Piccone, J M

The effect of cimetidine, an H/sub 2/-receptor blocking agent, on the secretion of /sup 99m/Tc-pertechnetate was studied in 11 dogs. In cimetidine-treated animals, there was increased retention of /sup 99m/Tc-pertechnetate by the gastric wall as compared with the untreated animals. The results indicate the potential use of cimetidine for enhanced visualization of Meckel's diverticulum, Barrett's esophagus, and the stomach, with /sup 99m/Tc-pertechnetate.

• Research Organization: Veterans Administration Medical and Regional Office Center, Wilmington, DE
• OSTI ID: 6502970
• Journal Information: Radiology; (United States), Vol. 139:3; Conference: 67. scientific assembly and annual meeting, Chicago, IL, USA, 15 Nov 1981
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
DIGESTIVE SYSTEM DISEASES
DIAGNOSIS
GASTRIC ACID
SECRETION
TECHNETIUM 99
RETENTION
BEAGLES
BIOLOGICAL EFFECTS
INHIBITION
ISOMERIC NUCLEI
PERTECHNETATES
STOMACH
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
DIGESTIVE SYSTEM
DISEASES
DOGS
GASTROINTESTINAL TRACT
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MATERIALS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
OXYGEN COMPOUNDS
RADIOISOTOPES
TECHNETIUM COMPOUNDS
TECHNETIUM ISOTOPES
TRANSITION ELEMENT COMPOUNDS
VERTEBRATES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics