Human hematopoietic colony-stimulating factors
Journal Article
·
· Science (Washington, D.C.); (United States)
The complementary DNAs and genes encoding the four major human myeloid growth factors - granulocyte colony-stimulating factor, macrophage colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, and interleukin-3 - have all been molecularly cloned. These DNA clones have proved valuable for studying the molecular biology of these important regulatory molecules as well as for the large-scale production of the recombinant growth factor proteins. These advances have led to a much better understanding of the role of the myeloid growth factors in regulating hematopoiesis in vivo that should soon find practical application in clinical medicine.
- Research Organization:
- Genetics Institute, Inc., Cambridge, MA
- OSTI ID:
- 6501809
- Journal Information:
- Science (Washington, D.C.); (United States), Journal Name: Science (Washington, D.C.); (United States) Vol. 236; ISSN SCIEA
- Country of Publication:
- United States
- Language:
- English
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