Mutagenicity, carcinogenicity, and teratogenicity of industrial pollutants
This book examines pollutants that present a possible risk to the genetic material of exposed workers. Current data is presented on heavy metals, insecticides, monomers, and halogenated hydrocarbon solvents. An attempt is made to correlate the molecular interaction mechanisms with test results for mutagenicity, carcinogenicity, and teratogenicity. Topics considered include cellular factors which modify the expression of mutagenic action into genetic lesions; the relation between mutation, repair, and chromosome aberration; chromosomal alterations and carcinogenesis; the mutagenicity, carcinogenicity, and teratogenicity of industrially used metals; the mutagenicity, carcinogenicity, and teratogenicity of insecticides; the mutagenicity, carcinogenicity, and teratogenicity of industrially important monomers; and the mutagenicity, carcinogenicity, and teratogenicity of halogenated hydrocarbon solvents. The examined compounds are compared in tables with regard to chemical properties, production, occurrence, accepted standards in the industry, and positive or negative results with different test systems.
- OSTI ID:
- 6497612
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
CARCINOGENESIS
CHEMICAL PROPERTIES
CHROMOSOMAL ABERRATIONS
ELEMENTS
GENETIC EFFECTS
HALOGENATED ALIPHATIC HYDROCARBONS
INDUSTRIAL WASTES
INSECTICIDES
METALS
MOLECULAR BIOLOGY
MONOMERS
MUTAGENESIS
MUTATIONS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
PATHOGENESIS
PESTICIDES
POLLUTANTS
RISK ASSESSMENT
STANDARDS
TERATOGENESIS
TESTING
WASTES
WORKING CONDITIONS