Multiple Pathway Exposure Factors (PEFs) associated with multimedia pollutants
Conference
·
OSTI ID:6496419
This paper describes methods for addressing several potential exposure pathways and provides a link between human exposure and chemical concentrations in multiple environmental media. This approach links environmental concentrations to human exposure through pathway-exposure factors (PEFs). The PEF incorporates information on human physiology, human behavior patterns, and environmental transport into a term that translates a unit concentration (in mg/m/sup 3/, mg/kg, or mg/L) in a specified environmental media (air, soil, or water) into daily exposure in mg/kg-d for a specified route (inhalation, ingestion, or dermal absorption). This process of exploring the data associated with human/environment interactions and proposing exposure models provides insight for risk-management activities. 11 refs., 1 fig., 3 tabs.
- Research Organization:
- Lawrence Livermore National Lab., CA (USA)
- DOE Contract Number:
- W-7405-ENG-48
- OSTI ID:
- 6496419
- Report Number(s):
- UCRL-99786; CONF-8808121-2; ON: DE89007222
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION
ANIMALS
BIOLOGICAL EFFECTS
BODY
ECOLOGICAL CONCENTRATION
ENVIRONMENTAL EXPOSURE PATHWAY
ENVIRONMENTAL TRANSPORT
EVALUATION
INGESTION
INHALATION
INTAKE
MAMMALS
MAN
MANAGEMENT
MASS TRANSFER
ORGANS
PHYSIOLOGY
POLLUTANTS
PRIMATES
PROGRAM MANAGEMENT
RISK ASSESSMENT
SKIN
VERTEBRATES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION
ANIMALS
BIOLOGICAL EFFECTS
BODY
ECOLOGICAL CONCENTRATION
ENVIRONMENTAL EXPOSURE PATHWAY
ENVIRONMENTAL TRANSPORT
EVALUATION
INGESTION
INHALATION
INTAKE
MAMMALS
MAN
MANAGEMENT
MASS TRANSFER
ORGANS
PHYSIOLOGY
POLLUTANTS
PRIMATES
PROGRAM MANAGEMENT
RISK ASSESSMENT
SKIN
VERTEBRATES