Case-control study of skin cancer in the rubber and tire manufacturing industry

Conference · Mon Sep 01 00:00:00 EDT 1986 · Am. J. Epidemiol.; (United States)

OSTI ID:6485932

Bourguet, C; Checkoway, H

A case-control study was conducted in the tire and rubber manufacturing industry to examine the association of squamous cell carcinoma of the skin with rubber manufacturing materials presumed to be contaminated by polycyclic aromatic hydrocarbons. Sixty-five cases were compared to 254 matched controls for exposure to carbon black, extender oils, lubricating oils, rubber solvents, and rubber stock. Both magnitude and duration of exposure were compared using data from company personnel records. Rubber stock and lubricating oils were associated with skin cancer. The overall relative risk (RR) associated with the highest level of rubber stock exposure was 2.2, and that associated with the highest level of lubricating oil exposure was 6.5. In analyses of subgroups of study members, the associations were strongest among workers who were born after 1900 (rubber stock, RR = 11.6; lubricating oil, RR = 4.5) and among workers whose skin cancer was diagnosed before age 70 years (rubber stock, RR = 23.2; lubricating oil, RR = 28.3).

• Research Organization: NEOUCOM, Rootstown, OH
• OSTI ID: 6485932
• Report Number(s): CONF-860694-
• Journal Information: Am. J. Epidemiol.; (United States), Vol. 124:3; Conference: Conference of the Society for Epidemiologic Research, Pittsburgh, PA, USA, 11 Jun 1986
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
POLYCYCLIC AROMATIC HYDROCARBONS
BIOLOGICAL EFFECTS
HEALTH HAZARDS
SKIN
NEOPLASMS
OCCUPATIONAL DISEASES
RUBBER INDUSTRY
TIRES
AROMATICS
BODY
DISEASES
HAZARDS
HYDROCARBONS
INDUSTRY
ORGANIC COMPOUNDS
ORGANS
560300* - Chemicals Metabolism & Toxicology