Case-control study of skin cancer in the rubber and tire manufacturing industry

Conference · Mon Sep 01 04:00:00 EDT 1986 · Am. J. Epidemiol.; (United States)

OSTI ID:6485932

Bourguet, C; Checkoway, H

A case-control study was conducted in the tire and rubber manufacturing industry to examine the association of squamous cell carcinoma of the skin with rubber manufacturing materials presumed to be contaminated by polycyclic aromatic hydrocarbons. Sixty-five cases were compared to 254 matched controls for exposure to carbon black, extender oils, lubricating oils, rubber solvents, and rubber stock. Both magnitude and duration of exposure were compared using data from company personnel records. Rubber stock and lubricating oils were associated with skin cancer. The overall relative risk (RR) associated with the highest level of rubber stock exposure was 2.2, and that associated with the highest level of lubricating oil exposure was 6.5. In analyses of subgroups of study members, the associations were strongest among workers who were born after 1900 (rubber stock, RR = 11.6; lubricating oil, RR = 4.5) and among workers whose skin cancer was diagnosed before age 70 years (rubber stock, RR = 23.2; lubricating oil, RR = 28.3).

• Research Organization: NEOUCOM, Rootstown, OH
• OSTI ID: 6485932
• Report Number(s): CONF-860694-
• Conference Information: Journal Name: Am. J. Epidemiol.; (United States) Journal Volume: 124:3
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AROMATICS
BIOLOGICAL EFFECTS
BODY
DISEASES
HAZARDS
HEALTH HAZARDS
HYDROCARBONS
INDUSTRY
NEOPLASMS
OCCUPATIONAL DISEASES
ORGANIC COMPOUNDS
ORGANS
POLYCYCLIC AROMATIC HYDROCARBONS
RUBBER INDUSTRY
SKIN
TIRES