The preservation of ovarian function in young women undergoing pelvic radiation therapy

Journal Article · Sun Jul 01 04:00:00 EDT 1984 · Gynecol. Oncol.; (United States)

DOI:https://doi.org/10.1016/0090-8258(84)90049-0· OSTI ID:6476723

Husseinzadeh, N; Nahhas, W A; Velkley, D E; Whitney, C W; Mortel, R

Because cervical carcinoma rarely metastasizes to the ovaries, it became logical to preserve ovarian function by the method of lateral ovarian transposition as part of the management of young women with this disease. This technique prevents castration should subsequent radiation therapy be planned or become necessary. Forty patients with carcinoma of the cervix or vagina underwent unilateral or bilateral ovarian transposition. Eighteen patients received radiation therapy. Of these, 16 had gonadotropin measurements and only 6 (37%) had levels elevated to the postmenopausal range. If patients whose ovaries were not shielded or who received paraaortic radiotherapy are excluded, then only two (17%) had elevated gonadotropin values. It is concluded that, if properly performed, lateral ovarian transposition and ovarian shielding will protect ovarian function in patients receiving pelvic radiotherapy.

• Research Organization: Department of Obstetrics and Gynecology, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey
• OSTI ID: 6476723
• Journal Information: Gynecol. Oncol.; (United States), Journal Name: Gynecol. Oncol.; (United States) Vol. 18:3; ISSN GYNOA
• Country of Publication: United States
• Language: English

Related Subjects

550603 -- Medicine-- External Radiation in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BODY
BODY AREAS
CARCINOMAS
DISEASES
FEMALE GENITALS
GONADS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
OVARIES
PELVIS
RADIATION PROTECTION
RADIOLOGY
RADIOTHERAPY
SURGERY
THERAPY