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Mutual stimulation by phosphatidylinositol-4-phosphate and myelin basic protein of their phosphorylation by the kinases solubilized from rat brain myelin

Journal Article · · Life Sci.; (United States)
Myelin basic protein and phosphatidylinositol-4-phosphate are phosphorylated in vitro by ATP and solubilized rat brain myelin. When both substrates are present together, the rate of phosphorylation of each is increased about eight-fold. It appears likely that the phosphate turnover of myelin basic protein and of phosphatidylinositol-4-phosphate are coupled in vivo.
Research Organization:
New York State Inst. for Basic Research in Developmental Disabilities, Staten Island
OSTI ID:
6472640
Journal Information:
Life Sci.; (United States), Journal Name: Life Sci.; (United States) Vol. 34:3; ISSN LIFSA
Country of Publication:
United States
Language:
English