Radiation carcinogenesis: Epidemiology and biological significance

Book · Sun Jan 01 04:00:00 EST 1984

OSTI ID:6468257

Boice, J D; Fraumeni, J F

Epidemiologic studies of populations exposed to radiation have led to the identification of a preventable cause of cancer, but in the long run perhaps the most important contribution of radiation studies will be to provide insights into the basic processes of human carcinogenesis. In this volume, key investigators of major epidemiologic projects summarize their observations to date, including information to help assess the effects of low-level exposures. Experimentalists and theorists emphasize the relevance of laboratory and epidemiologic data in elucidating carcinogenic risks and mechanisms in man. This volume was prepared with several objectives in mind: (a) organize and synthesize knowledge on radiation carcinogenesis through epidemiologic and experimental approaches; (b) illustrate and explore ways of utilizing this information to gain insights into the fundamental mechanisms of cancer development; (c) stimulate the formation of hypotheses suited to experimental or epidemiologic testing, theoretical modeling, and multidisciplinary approaches; and (d) identify recent advances that clarify dose-response relationships and the influence of low-dose exposures, provide leads to carcinogenic mechanisms and host-environmental interactions, and suggest strategies for future research and preventive action.

• OSTI ID: 6468257
• Country of Publication: United States
• Language: English

Related Subjects

560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSTRACTS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
CARCINOGENESIS
DISEASES
DOCUMENT TYPES
DOSE-RESPONSE RELATIONSHIPS
DOSES
EPIDEMIOLOGY
HUMAN POPULATIONS
IONIZING RADIATIONS
IRRADIATION
LEADING ABSTRACT
LOW DOSE IRRADIATION
MEETINGS
NEOPLASMS
PATHOGENESIS
POPULATIONS
RADIATION DOSES
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
RESEARCH PROGRAMS
REVIEWS