Treatment of cancer of the pancreas by intraoperative electron beam therapy: physical and biological aspects

Journal Article · Sun Jan 01 04:00:00 EST 1989 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(89)90036-9· OSTI ID:6467825

Bagne, F R; Dobelbower, Jr, R R; Milligan, A J; Bronn, D G

Radiation therapy has had a significant and an expanded role in the management of cancer of the pancreas during the last decade. In particular, for locally advanced disease, radiation therapy has improved the median survival of patients to 1 year. Intraoperative electron beam therapy has been applied to unresectable and resectable pancreatic cancer in an attempt to enhance local control of disease and to improve patient survival. This paper presents a survey of the role of radiation therapy in treatment of cancer of the pancreas, provides information on the radiobiological aspects of this treatment modality and details the physical and dosimetric characteristics of intraoperative radiation therapy with electrons. Presented are the design specifics of an applicator system, central axis beam data, applicator parameters, dose distribution data, shielding, treatment planning and means of verification. Emphasis is placed on the collaboration and cooperation necessary for all members of the intraoperative radiation therapy team including surgeons, radiation therapists, medical physicists, anesthesiologists, technologists, and nurses.29 references.

• Research Organization: Medical College of Ohio, Toledo (USA)
• OSTI ID: 6467825
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 16:1; ISSN IOBPD
• Country of Publication: United States
• Language: English

Related Subjects

550600 -- Medicine
550603* -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BEAMS
BODY
DIGESTIVE SYSTEM
DISEASES
DOCUMENT TYPES
ELECTRON BEAMS
ENDOCRINE GLANDS
FEDERAL REGION V
GLANDS
LEPTON BEAMS
MEDICINE
NEOPLASMS
NORTH AMERICA
NUCLEAR MEDICINE
OHIO
ORGANS
PANCREAS
PARTICLE BEAMS
PLANNING
RADIOLOGY
RADIOTHERAPY
REVIEWS
SURGERY
SURVIVAL CURVES
THERAPY
USA