Precision radiotherapy for cancer of the pancreas: technique and results. [Photons and electrons]

Conference · Mon Sep 01 04:00:00 EDT 1980 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

OSTI ID:6880416

Dobelbower, Jr, R R; Borgelt, B B; Strubler, K A; Kutcher, G J; Suntharalingam, N

Forty patients with locally extensive, unresectable adenocarcinoma of the pancreas received precision high dose (PHD) radiation therapy with a 45 MeV betatron. PHD radiotherapy was generally well tolerated. During treatment, only 7 patients experienced significant nausea, vomiting, diarrhea or anorexia. Late gastrointestinal radiation reactions were observed in 7 patients. Twelve patients received adjuvant chemotherapy. The projected survival of patients with unresectable pancreatic cancer treated with PHD radiotherapy is comparable to that of patients with resectable disease operated on for cure. The projected one year survival rate is 49%.

• Research Organization: Thomas Jefferson Univ. Hospital, Philadelphia, PA
• OSTI ID: 6880416
• Conference Information: Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Journal Volume: 6:9
• Country of Publication: United States
• Language: English

Related Subjects

550603 -- Medicine-- External Radiation in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACCELERATORS
AMIDES
AMINES
ANTIMETABOLITES
ANTIMITOTIC DRUGS
AZINES
BEAMS
BETATRONS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
CARBONIC ACID DERIVATIVES
CHEMOTHERAPY
CYCLIC ACCELERATORS
DELAYED RADIATION EFFECTS
DIARRHEA
DIGESTIVE SYSTEM
DISEASES
DRUGS
EARLY RADIATION EFFECTS
ELECTRON BEAMS
ENDOCRINE GLANDS
ENERGY RANGE
FLUOROURACILS
GASTROINTESTINAL TRACT
GLANDS
GUANINE
HEMORRHAGE
HETEROCYCLIC COMPOUNDS
HYDROXY COMPOUNDS
INFLAMMATION
LEPTON BEAMS
MEDICINE
METASTASES
MEV RANGE
MEV RANGE 10-100
NAUSEA
NEOPLASMS
NITROSO COMPOUNDS
NUCLEAR MEDICINE
ORGANIC COMPOUNDS
ORGANIC FLUORINE COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PANCREAS
PARTICLE BEAMS
PATHOLOGICAL CHANGES
PATIENTS
PHOTON BEAMS
PURINES
PYRIMIDINES
RADIATION EFFECTS
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
SEPTICEMIA
SIDE EFFECTS
SURVIVAL TIME
SYMPTOMS
THERAPY
URACILS
UREA
VOMITING