Ultraviolet excimer laser ablation: the effect of wavelength and repetition rate on in vivo guinea pig skin

Journal Article · Mon Jun 01 00:00:00 EDT 1987 · J. Invest. Dermatol.; (United States)

DOI:https://doi.org/10.1111/1523-1747.ep12470471· OSTI ID:6464428

Morelli, J; Kibbi, A G; Farinelli, W; Boll, J; Tan, O T

Multiple dermatologic conditions that are currently treated with traditional cold-knife surgery are amenable to laser therapy. The ideal surgical treatment would be precise and total removal of abnormal tissue with maximal sparing of remaining structures. The ultraviolet (UV) excimer laser is capable of such precise tissue removal due to the penetration depth of 193 nm and 248 nm irradiation of 1 micron per pulse. This type of ablative tissue removal requires a high repetition rate for efficient lesional destruction. Excimer laser radiation at 193 nm is capable of high repetition rates, which are necessary while 248 nm radiation causes increasing nonspecific thermal injury as the laser repetition rate is increased.

• Research Organization: Univ. of Colorado Medical Center, Denver
• OSTI ID: 6464428
• Journal Information: J. Invest. Dermatol.; (United States), Journal Name: J. Invest. Dermatol.; (United States) Vol. 6; ISSN JIDEA
• Country of Publication: United States
• Language: English

Related Subjects

550600 -- Medicine
560400* -- Other Environmental Pollutant Effects
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BODY
ELECTROMAGNETIC RADIATION
GUINEA PIGS
LASER RADIATION
LASERS
MAMMALS
MEDICINE
ORGANS
RADIATIONS
RODENTS
SKIN
SURGERY
ULTRAVIOLET RADIATION
VERTEBRATES
WAVELENGTHS