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U.S. Department of Energy
Office of Scientific and Technical Information

Labeled phosphonic acid compositions for investigations of in vivo deposits of calcium

Patent ·
OSTI ID:6456794
The composition and methodology associated with the formulation of a halogenated phosphonic acid labeled in the ring moiety are disclosed having the formula: HO-P(=O)(-OH)-C(-R/sub 1/)(-R/sub 2/)-P(=O)(-OH)-OH wherein R/sub 1/ is aryl and is labeled with a halogen and R/sub 2/ is hydrogen, alkyl, alkenyl, amino, benzyl, hydroxyl-CH/sub 2/PO/sub 3/H -CH/sub 2/CH/sub 2/PO/sub 3/H/sub 2/ and is labeled with halogen. The compositions are especially useful for scanning investigations of in vivo deposits of calcium.
Assignee:
The Massachusetts General Hospital
Patent Number(s):
US 4515766
OSTI ID:
6456794
Country of Publication:
United States
Language:
English