An in-phantom comparison of neutron fields for BNCT

Conference · Thu Jan 01 04:00:00 EST 1998

OSTI ID:645469

Woollard, J E; Blue, T E ^[1]; Capala, J ^[2]

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1. Ohio State Univ., Columbus, OH (United States). Nuclear Engineering Program
2. Brookhaven National Lab., Upton, NY (United States). Medical Dept.

Previously, the authors have developed the in-phantom neutron field assessment parameters T and D (Tumor) for the evaluation of epithermal neutron fields for use in BNCT. These parameters are based on an energy-spectrum-dependent neutron normal-tissue RBE and the treatment planning methodology of Gahbauer and his co-workers, which includes the effects of dose fractionation. In this paper, these neutron field assessment parameters were applied to The Ohio State University (OSU) design of an Accelerator Based Neutron Source (ABNS) (hereafter called the OSU-ABNS) and the Brookhaven Medical Research Reactor (BMRR) epithermal neutron beam (hereafter called the BMRR-ENB), in order to judge the suitability of the OSU-ABNS for BNCT. The BMRR-ENB was chosen as the basis for comparison because it is presently being used in human clinical trials of BNCT and because it is the standard to which other neutron beams are most often compared.

• Research Organization: Brookhaven National Lab., Upton, NY (United States)
• Sponsoring Organization: USDOE Office of Energy Research, Washington, DC (United States)
• DOE Contract Number: AC02-76CH00016
• OSTI ID: 645469
• Report Number(s): BNL--65162; CONF-980606--; ON: DE98004229
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
BRAIN
COMPARATIVE EVALUATIONS
NEOPLASMS
NEUTRON CAPTURE THERAPY
PHANTOMS
RADIATION DOSES