An in-phantom comparison of neutron fields for BNCT

Journal Article · Tue Sep 01 04:00:00 EDT 1998 · Transactions of the American Nuclear Society

OSTI ID:644235

Woollard, J E; Blue, T E ^[1]; Capala, J ^[2]

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1. Ohio State Univ., Columbus, OH (United States)
2. Brookhaven National Lab., Upton, NY (United States)

Previously, the authors developed the in-phantom neutron field assessment parameters T and D{sub tumor} for the evaluation of epithermal neutron fields for use in boron neutron capture therapy (BNCT). These parameters are based on an energy-spectrum-dependent neutron normal-tissue relative biological effectiveness (RBE) and the treatment planning methodology of Gahbauer and his co-workers, which includes the effects of dose fractionation. In this paper, these neutron field assessment parameters were applied to the Ohio State University (OSU) design of an accelerator-based neutron source (ABNS) and the Brookhaven Medical Research Reactor (BMRR) epithermal neutron beam (ENB) in order to judge the suitability of the OSU-ABNS for BNCT. The BMRR-ENB was chosen as the basis for comparison because it is being used in human clinical trials of BNCT and because it is the standard to which other neutron beams are most often compared.

• OSTI ID: 644235
• Report Number(s): CONF-980606--
• Journal Information: Transactions of the American Nuclear Society, Journal Name: Transactions of the American Nuclear Society Vol. 78; ISSN TANSAO; ISSN 0003-018X
• Country of Publication: United States
• Language: English

Related Subjects

43 PARTICLE ACCELERATORS
55 BIOLOGY AND MEDICINE
BASIC STUDIES
ACCELERATOR FACILITIES
BORON
COMPARATIVE EVALUATIONS
MRR REACTOR
NEUTRON BEAMS
NEUTRON CAPTURE THERAPY
NEUTRON SOURCES
PERFORMANCE
RBE