Formaldehyde: evidence of carcinogenicity
- National Inst. for Occupational Safety and Health, Rockville, MD
The National Institute for Occupational Safety and Health (NIOSH) recommends that formaldehyde be handled as a potential occupational carcinogen and that appropriate controls be used to reduce worker exposure. These recommendations are based primarily on a Chemical Industry Institute of Toxicology (CIIT) study in which laboratory rats and mice exposed to formaldehyde vapor developed nasal cancer, and are supported by a New York University study where rats exposed to a mixture of formaldehyde and hydrochloric acid vapors developed nasal cancer. Formaldehyde has also been shown to be a mutagen in several short-term laboratory studies. In addition to the carcinogenic potential, other adverse health effects caused by formaldehyde are described. NIOSH requests that producers and distributors of formaldehyde, and of substances and materials containing formaldehyde, give this information to their employees and customers, and that professional and trade associations and unions inform their members.
- OSTI ID:
- 6453336
- Journal Information:
- Am. Ind. Hyg. Assoc. J.; (United States), Journal Name: Am. Ind. Hyg. Assoc. J.; (United States) Vol. 42:7; ISSN AIHAA
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
99 GENERAL AND MISCELLANEOUS
ALDEHYDES
ANIMALS
BODY
BODY AREAS
CARCINOGENESIS
DISEASES
FACE
FORMALDEHYDE
HAZARDS
HEAD
HEALTH HAZARDS
INHALATION
INTAKE
MAMMALS
MICE
MUTAGENS
NEOPLASMS
NOSE
OCCUPATIONAL SAFETY
ORGANIC COMPOUNDS
PATHOGENESIS
PERSONNEL
RATS
RESPIRATORY SYSTEM
RODENTS
SAFETY
TOXICITY
VERTEBRATES