Intra-abdominal recurrence of colorectal cancer detected by radioimmunoguided surgery (RIGS system)

Journal Article · Sun Jan 01 04:00:00 EST 1989 · Arch. Surg. (Chicago); (United States)

DOI:https://doi.org/10.1001/archsurg.1989.01410010065014· OSTI ID:6443838

Sardi, A; Workman, M; Mojzisik, C; Hinkle, G; Nieroda, C; Martin, Jr, E W

Since 1986, 32 patients with metastatic colorectal cancer have undergone second-look radioimmunoguided surgery (RIGS system). The primary tumor was located in the right and transverse colon in 11 patients, left and sigmoid colon in 16, and rectum in five. The carcinoembryonic antigen level was elevated in 30 patients (94%); all patients underwent a computed tomographic scan of the abdomen and pelvis. The overall sensitivity of the computed tomographic scan was 41% (abdomen other than liver, 27%; liver, 58%; and pelvis, 22%). The RIGS system identified recurrent tumor in 81% of the patients. The most common site of metastasis was the liver (41%), independent of the primary location. Local/regional recurrences alone accounted for 40% of all recurrences. In six patients (18%), recurrent tumor was found only with the RIGS system. The RIGS system is more dependable in localizing clinically obscure metastases than other methods, and carcinoembryonic antigen testing remains the most accurate preoperative method to indicate suspected recurrences.

• Research Organization: Ohio State Univ. College of Medicine, Columbus (USA)
• OSTI ID: 6443838
• Journal Information: Arch. Surg. (Chicago); (United States), Journal Name: Arch. Surg. (Chicago); (United States) Vol. 124:1; ISSN ARSUA
• Country of Publication: United States
• Language: English

Related Subjects

550600 -- Medicine
550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ANTIGENS
BODY
CARCINOEMBRYONIC ANTIGEN
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
GASTROINTESTINAL TRACT
INTESTINES
LARGE INTESTINE
MEDICINE
METASTASES
NEOPLASMS
ORGANS
PATIENTS
RECTUM
SURGERY
TOMOGRAPHY