Air-sampling and analytical method for 4,4'-methylenebis(2-chloroaniline)

Journal Article · Sun Dec 31 23:00:00 EST 1978 · Anal. Chem.; (United States)

DOI:https://doi.org/10.1021/ac50037a012· OSTI ID:6436147

Rappaport, S M; Morales, R

A sampling and analytical method is described for the determination of airborne exposures of individuals to the carcinogen, 4,4'-methylenebis(2-chloroaniline), known as MOCA. The personal sampler employs a filter to collect particulate MOCA followed by a bed of silica gel to remove the vapors. MOCA is extracted from the sampler stages with methanol and a 10-..mu..L aliquot is injected into an HPLC operating with a reverse-phase system. The UV detector (254 nm) allows quantitation of 3 ng of MOCA corresponding to 0.15 ..mu..g/sample. Precision levels were determined to be 9.2% at 1.5 ..mu..g/sample and 14% at 0.15 ..mu..g/sample. 7 figures, 3 tables..

• Research Organization: Univ. of California, Los Alamos, NM
• OSTI ID: 6436147
• Journal Information: Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 51:1; ISSN ANCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102 -- Chemical & Spectral Procedures
500200* -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
560306 -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADSORBENTS
AEROSOLS
AIR POLLUTION
AIR POLLUTION MONITORS
AIR SAMPLERS
ALCOHOLS
AMINES
CARCINOGENS
CHEMICAL ANALYSIS
CHROMATOGRAPHY
COLLOIDS
DISPERSIONS
EXTRACTION
FILTERS
HYDROXY COMPOUNDS
LABORATORY EQUIPMENT
LIQUID COLUMN CHROMATOGRAPHY
MEDIUM PRESSURE
MEDIUM TEMPERATURE
METHANOL
MONITORING
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
POLLUTION
PRESSURE DEPENDENCE
QUANTITATIVE CHEMICAL ANALYSIS
SAMPLERS
SENSITIVITY
SEPARATION PROCESSES
SILICA GEL
SOLS
SOLVENT EXTRACTION
SPECTRA
TEMPERATURE DEPENDENCE
TRACE AMOUNTS
ULTRAVIOLET SPECTRA