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Special hazard review with control recommendations for 4,4'-methylenebis(2-chloroaniline)

Technical Report ·
OSTI ID:5637172

The report reviews current toxicity information on 4,4'-Methylenebis (2-chloroaniline) and makes control recommendations. 4,4'-Methylenebis(2-chloroaniline) has the formula C13H12C12N2. It is commercially important as a curing agent for diisocyanate-based polymers (polyurethanes) and epoxy resin systems. 4,4'-Methylenebis(2-chloroaniline) is used to vary the hardness, flexibility, and impact strength of these products. 4,4'-Methylenebis(2-chloroaniline) has been manufactured commercially in the U.S. since 1956. Above 200 C, 4,4'-Methylenebis(2-chloroaniline), releases irritant and toxic vapors (primarily ortho-chloroaniline). NIOSH estimated through a national survey that in the early 1970's approximately 55,000 U.S. workers were potentially exposed to 4,4'-Methylenebis(2-chloroaniline). The majority of these workers were employed in small-to-medium sized establishments where occupational health services may not have been readily available. This review provides an examination of information available in 1973 and a more detailed presentation of recent studies along with recommendations for control of workplace exposures to 4,4-Methylenebis(2-chloroaniline).

Research Organization:
National Inst. for Occupational Safety and Health, Cincinnati, OH (USA)
OSTI ID:
5637172
Report Number(s):
PB-297822
Country of Publication:
United States
Language:
English

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Related Subjects

560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
570000 -- Health & Safety
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
99 GENERAL AND MISCELLANEOUS
CHRONIC EXPOSURE
DOCUMENT TYPES
FLUIDS
GASES
HAZARDOUS MATERIALS
INDUSTRIAL MEDICINE
MEDICINE
OCCUPATIONAL SAFETY
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC POLYMERS
PETROCHEMICALS
PETROLEUM PRODUCTS
POLYMERS
RECOMMENDATIONS
RESINS
REVIEWS
SAFETY
TOXICITY
VAPORS