Denatured albumin complexes for radioscintigraphic imaging and evaluation of reticuloendothelial systems
Patent
·
OSTI ID:6430917
Small sized material (less than 0.2 mu m, preferably less than 1 mu m) comprising a complex of (1) denatured albumi particularly human serum albumin and (2) a metal reducing agent, particularly a stannous reducing agent, preferably formed in the presence of a stabilizing ligand, which complex, when labelled with technetium-99m provides an excellent agent for imaging or otherwise evaluating reticuloendothelial systems (res) and/or components thereof, particularly the bone marrow, liver and/or lymphatic system; methods of making and using the same; a complex (physical or chemical) of technetium-99m with such materials and methods of using such latter complex.
- Assignee:
- New England Nuclear Corp
- Patent Number(s):
- US 4337240
- OSTI ID:
- 6430917
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
551001* -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ALBUMINS
ANIMAL TISSUES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COMPLEXES
HOURS LIVING RADIOISOTOPES
IMAGE PROCESSING
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIGANDS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
PROCESSING
PROTEINS
RADIOISOTOPES
RETICULOENDOTHELIAL SYSTEM
TECHNETIUM 99
TECHNETIUM ISOTOPES
TISSUES
YEARS LIVING RADIOISOTOPES
59 BASIC BIOLOGICAL SCIENCES
ALBUMINS
ANIMAL TISSUES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COMPLEXES
HOURS LIVING RADIOISOTOPES
IMAGE PROCESSING
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIGANDS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
PROCESSING
PROTEINS
RADIOISOTOPES
RETICULOENDOTHELIAL SYSTEM
TECHNETIUM 99
TECHNETIUM ISOTOPES
TISSUES
YEARS LIVING RADIOISOTOPES