Evaluation of brain edema using magnetic resonance proton relaxation times

Journal Article · Mon Jan 01 04:00:00 EST 1990 · Advances in Neurology; (USA)

OSTI ID:6422039

Fu, Y; Tanaka, K; Nishimura, S ^[1]

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1. Baba Memorial Hospital, Osaka (Japan)

Experimental and clinical studies on the evaluation of water content in cases of brain edema were performed in vivo, using MR proton relaxation times (longitudinal relaxation time, T1; transverse relaxation time, T2). Brain edema was produced in the white matter of cats by the direct infusion method. The correlations between proton relaxation times obtained from MR images and the water content of white matter were studied both in autoserum-infused cats and in saline-infused cats. The correlations between T1 as well as T2 and the water content in human vasogenic brain edema were also examined and compared with the data obtained from the serum group. T1 and T2 showed good correlations with the water content of white matter not only in the experimental animals but also in the clinical cases. The quality of the edema fluid did not influence relaxation time and T1 seemed to represent almost solely the water content of the tissue. T2, however, was affected by the nature of existence of water and was more sensitive than T1 in detecting extravasated edema fluid. It seems feasible therefore to evaluate the water content of brain edema on the basis of T1 values.

• OSTI ID: 6422039
• Journal Information: Advances in Neurology; (USA), Journal Name: Advances in Neurology; (USA) Vol. 52; ISSN 0091-3952; ISSN ADNRA
• Country of Publication: United States
• Language: English

Related Subjects

550600* -- Medicine
62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMALS
BARYONS
BODY
BRAIN
CATS
CENTRAL NERVOUS SYSTEM
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
EDEMA
ELEMENTARY PARTICLES
FERMIONS
HADRONS
MAGNETIC RESONANCE
MAMMALS
MAN
NERVOUS SYSTEM
NERVOUS SYSTEM DISEASES
NMR IMAGING
NUCLEAR MAGNETIC RESONANCE
NUCLEONS
ORGANS
PATHOLOGICAL CHANGES
PRIMATES
PROTONS
RESONANCE
SYMPTOMS
VERTEBRATES