Allyl chloride: the mutagenic activity of its photooxidation products

Journal Article · Mon Jun 01 00:00:00 EDT 1987 · Environ. Sci. Technol.; (United States)

DOI:https://doi.org/10.1021/es00160a007· OSTI ID:6412486

Shepson, P B; Kleindienst, T E; Nero, C M; Hodges, D N; Cupitt, L T; Claxton, L D

Irradiations of C/sub 3/H/sub 5/Cl/NO/sub x/, C/sub 3/H/sub 5/Cl/C/sub 2/H/sub 6//NO/sub x/, and C/sub 2/H/sub 6//NO/sub x/ mixtures were conducted in a 22.7-m/sup 3/ Teflon smog chamber, operated in a static mode. The irradiated mixtures were tested for mutagenic activity by periodically exposing Salmonella typhimurium strain TA100 to the smog chamber effluent during the irradiation. The allyl chloride photooxidation products' total mutagenic activity was found to be dramatically dependent on the presence of Cl atom reaction products. In the absence of C/sub 2/H/sub 6/, which is used as a Cl atom scavenger, the observed mutagenic activity of the irradiated C/sub 3/H/sub 5/Cl/NO/sub x/ mixture at long extent of reaction was 13 revertants-plate/sup -1/-h/sup -1/-(ppb C/sub 3/H/sub 5/Cl consumed)/sup -1/. However, when sufficient C/sub 2/H/sub 6/ was present to remove all Cl atoms, the observed mutagenic activity for C/sub 3/H/sub 5/Cl photooxidation products was 1.4 revertants-plate/sup -1/-h/sup -1/-(ppb C/sub 3/H/sub 5/Cl consume)/sup -1/. Under conditions of excess C/sub 2/H/sub 6/, the mixture is approximately 30 times more mutagenic than that previously observed for the mutagenic activity of the photooxidation products of propylene, the nonchlorinated analogue of allyl chloride. The observed mutagenic activity in the presence of excess C/sub 2/H/sub 6/ is consistent with the total response caused by chloroacetaldehyde, a primary C/sub 3/H/sub 5/Cl photooxidation product.

• Research Organization: Northrop Services, Inc., Research Triangle Park, NC
• OSTI ID: 6412486
• Journal Information: Environ. Sci. Technol.; (United States), Journal Name: Environ. Sci. Technol.; (United States) Vol. 21:6; ISSN ESTHA
• Country of Publication: United States
• Language: English

Related Subjects

500200* -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
ALKYL RADICALS
ALLYL RADICALS
ATMOSPHERIC CHEMISTRY
BACTERIA
CHEMICAL REACTIONS
CHEMISTRY
CHLORINE
CLOUD CHAMBERS
ELEMENTS
GAS TRACK DETECTORS
HALOGENS
MEASURING INSTRUMENTS
MICROORGANISMS
MUTAGENESIS
MUTATIONS
NONMETALS
PHOTOCHEMICAL OXIDANTS
PHOTOCHEMICAL REACTIONS
PHOTOCHEMISTRY
RADIATION DETECTORS
RADICALS
SALMONELLA
SALMONELLA TYPHIMURIUM
SMOG