Mutagenic activity of the products of ozone reaction with propylene in the presence and absence of nitrogen dioxide

Journal Article · Thu Oct 31 23:00:00 EST 1985 · Environ. Sci. Technol.; (United States)

DOI:https://doi.org/10.1021/es00141a013· OSTI ID:5533835

Shepson, P B; Kleindienst, T E; Edney, E O; Cuplitt, L T; Claxton, L D

This study was performed to determine if propylene reaction with ozone could account for the large mutagenic activity we have observed in irradiated propylene/NO/sub x/ mixtures. In a 22.7-m/sup 3/ flow mode smog chamber, 5.4 ppm of propylene was allowed to react with 0.9 ppm of ozone either in the presence or in the absence of 0.2 ppm of nitrogen dioxide (at 25 /sup 0/C in the dark). The steady-state reactant and product distribution was then tested for total mutagenic activity by exposing Salmonella typhimurium strain TA100 to the gas-phase chamber effluent. The total product dosage in the test plates was varied by exposing them for 0, 5, 10, 15, and 20 h. Salmonella typhimurium survivor levels were obtained at each length of exposure. The number of revertants per plate increased at a rate of approx. 4-5 per hour, while the survivor level decreased throughout the exposure. Most of the total mutagenic activity can be accounted for by the presence of formaldehyde. The total mutagenic activity observed was, however, much smaller than that observed in the irradiated propylene/NO/sub x/ system, for comparable amounts of propylene consumed.

• Research Organization: Northrop Services, Inc., Research Triangle Park, NC
• OSTI ID: 5533835
• Journal Information: Environ. Sci. Technol.; (United States), Journal Name: Environ. Sci. Technol.; (United States) Vol. 19:1; ISSN ESTHA
• Country of Publication: United States
• Language: English

Related Subjects

500200* -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
ALKENES
BACTERIA
BIOLOGICAL EFFECTS
CHALCOGENIDES
CHEMICAL REACTION YIELD
HYDROCARBONS
MICROORGANISMS
MUTAGENESIS
MUTAGENS
MUTATIONS
NITROGEN COMPOUNDS
NITROGEN DIOXIDE
NITROGEN OXIDES
ORGANIC COMPOUNDS
OXIDES
OXYGEN COMPOUNDS
OZONE
PROPYLENE
SALMONELLA
SALMONELLA TYPHIMURIUM
YIELDS