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Experimental chemotherapy and radiotherapy to paratesticular rhabdomyosarcoma

Journal Article · · J. Urol.; (United States)
OSTI ID:6395403
Experimental chemotherapy and radiotherapy were tried in transplanted tumors derived from a paratesticular embryonal rhabdomyosarcoma. There was no significant difference on the therapeutic effect between a combination chemotherapy composed of vincristine, actinomycin D and cyclophosphamide, so-called VAC regimen, and a single therapy of radiation. However, morphologic analyses suggest that VAC is effective in embryonal rhabdomyosarcomas in which undifferentiated rhabdomyoblasts predominate, while radiotherapy is preferable for those containing variously differentiated rhabdomyoblasts.
Research Organization:
Niigata Univ. School of Medicine (Japan)
OSTI ID:
6395403
Journal Information:
J. Urol.; (United States), Journal Name: J. Urol.; (United States) Vol. 141:1; ISSN JOURA
Country of Publication:
United States
Language:
English