Management of squamous cell carcinoma in cervical lymph nodes in the clinical absence of primary lesion by combined surgery and irradiation. [/sup 60/Co]
Journal Article
·
· Cancer; (United States)
OSTI ID:6395025
Sixty-three patients who had either previously treated primary tumors or unknown primary tumors and developed metastatic cervical adenopathy in their previously untreated necks received the combination of surgery and megavoltage irradiation. Within two years, 12 patients died of intercurrent disease, nine patients died with distant metastastases only, and five patients had disease recur at a primary site. The remaining 37 patients were evaluable for control of neck disease; 26 patients had previous treatment to a primary head and neck cancer that was under control at the time cervical adenopathy was treated; and 11 patients had an unknown primary tumor that was believed to be in the head and neck area. The combination of pre- or postoperative irradiation and surgery controlled neck disease in 86% of the evaluable patients. Because of the extent of neck disease, these patients would have been at a high risk of failure in the treated area if only a single modality of treatment were uognostic variables, in addition to treatment, were pretreatment performance status and pretreatment CEA level. The toxic reactions related to the treatment are discussed.
- Research Organization:
- Univ. of Texas, Houston
- OSTI ID:
- 6395025
- Journal Information:
- Cancer; (United States), Journal Name: Cancer; (United States) Vol. 48:8; ISSN CANCA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550603* -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
BODY AREAS
CARCINOMAS
COBALT 60
COBALT ISOTOPES
DISEASES
ELECTROMAGNETIC RADIATION
ELECTRONS
ELEMENTARY PARTICLES
ENERGY RANGE
EVALUATION
FERMIONS
GAMMA RADIATION
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LEPTONS
LYMPH NODES
LYMPHATIC SYSTEM
MEDICINE
METASTASES
MEV RANGE
MEV RANGE 01-10
MINUTES LIVING RADIOISOTOPES
NECK
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
PATIENTS
RADIATIONS
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SURGERY
THERAPY
YEARS LIVING RADIOISOTOPES
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
BODY AREAS
CARCINOMAS
COBALT 60
COBALT ISOTOPES
DISEASES
ELECTROMAGNETIC RADIATION
ELECTRONS
ELEMENTARY PARTICLES
ENERGY RANGE
EVALUATION
FERMIONS
GAMMA RADIATION
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LEPTONS
LYMPH NODES
LYMPHATIC SYSTEM
MEDICINE
METASTASES
MEV RANGE
MEV RANGE 01-10
MINUTES LIVING RADIOISOTOPES
NECK
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
PATIENTS
RADIATIONS
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SURGERY
THERAPY
YEARS LIVING RADIOISOTOPES