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Left ventricular stroke volume determinations from radionuclide ventriculograms: the effects of photon attenuation

Journal Article · · Radiology; (United States)
To improve the accuracy of scintigraphic ventricular volume determination, which is limited by photon attenuation between the heart and the gamma camera, a method was developed for directly measuring the photon attenuation of radioactivity delivered as a bolus through a Swan-Ganz catheter into the right atrium. Comparison of the count rate recovered from this bolus with the total ex vivo measured activity determined by imaging an aliquot of the administered activity allowed calculation of the attenuation factor. Left ventricular stroke volumes determined scintigraphically by the count method in gated blood pool studies and then corrected with this attention factor correlated well with stroke volumes determined from thermodilution cardiac output and heart rate. The results indicate that correction for photon attenuation is needed for accurage measurement of left ventricular volumes.
Research Organization:
Univ. of California, Los Angeles
DOE Contract Number:
AC03-76SF00012
OSTI ID:
6385786
Journal Information:
Radiology; (United States), Journal Name: Radiology; (United States) Vol. 153:1; ISSN RADLA
Country of Publication:
United States
Language:
English