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Enhanced sensitivity of Escherichia coli umuC to photodynamic inactivation by angelicin (isopsoralen)

Journal Article · · J. Bacteriol.; (United States)
OSTI ID:6378833
Escherichia coli umuC cells were inactivated four times more rapidly than umuC+ cells by angelicin (a monofunctional psoralen) plus near-UV irradiation. With other DNA-damaging treatments, either no or much smaller differences in sensitivity were observed. These results show that functions associated with the UmuC+ phenotype contribute to the repair (or tolerance) of some categories of DNA damage more efficiently than others.
OSTI ID:
6378833
Journal Information:
J. Bacteriol.; (United States), Journal Name: J. Bacteriol.; (United States) Vol. 3; ISSN JOBAA
Country of Publication:
United States
Language:
English