Serum myoglobin determination laboratory and clinical evaluation. [/sup 125/I radioimmunoassay]

Journal Article · Thu Feb 01 04:00:00 EST 1979 · J. Nucl. Med.; (United States)

OSTI ID:6371809

Sonnemaker, R E; Daniels, D L; Craig, W E; Floyd, J L; Bode, R F

Quality assurance examination of a commercially available radioimmunoassay kit for determination of serum myoglobin level confirmed the measurement to be accurate, precise, and reproducible under all assay performance variables. Initial clinical evaluation in patients admitted to the Coronary Care Unit revealed comparable diagnostic parameters and earlier detection when compared with the present standard indicator of myocardial necrosis, creatine phosphokinase MB isoenzyme. Interpretation that an elevated myoglobin reflects acute myocardial infarction should be made only in the appropriate clinical context.

• Research Organization: Army Medical Center, El Paso, TX
• OSTI ID: 6371809
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 20:2; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BLOOD SERUM
CARBOXYLIC ACIDS
CARDIOVASCULAR DISEASES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC USES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
GLOBIN
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
IMMUNE SERUMS
INTERMEDIATE MASS NUCLEI
IODINE 125
IODINE ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
LABELLED COMPOUNDS
MYOCARDIAL INFARCTION
MYOGLOBIN
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PATIENTS
PIGMENTS
PORPHYRINS
PROTEINS
RADIOASSAY
RADIOIMMUNOASSAY
RADIOISOTOPES
TRACER TECHNIQUES
USES