New detection methods and techniques with applications in liquid chromatography

Technical Report · Tue Oct 01 04:00:00 EDT 1985

OSTI ID:6341476

Wilson, S A

These new analytic techniques are described. (1) a three-dimensional detector which simultaneously monitors the refractive index, absorbance and fluorescence is based on the coupling of a tightly focused laser beam and microbore column liquid chromatography. (2) an absorbance detector which allows one to make differential absorbance measurements is based on Michelson interferometry with a laser. (3) A novel detection method which is based on the combination of an absorbance detector and an electrical conductivity detector allows one to detect nonabsorbing analytes. In this scheme analytes can be quantified without the need of standards. 63 refs., 13 figs., 2 tabs. (WRF)

• Research Organization: Iowa State Univ. of Science and Technology, Ames (USA). Dept. of Chemistry
• DOE Contract Number: W-7405-ENG-82
• OSTI ID: 6341476
• Report Number(s): IS-T-1190; ON: DE86002109
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400301* -- Organic Chemistry-- Chemical & Physicochemical Properties-- (-1987)
ABSORPTION
ACETATES
ALKALI METAL COMPOUNDS
AROMATICS
AZOLES
BENZENE
BENZOIC ACID
BROMINE COMPOUNDS
CARBOXYLIC ACID SALTS
CARBOXYLIC ACIDS
CHLORINATED AROMATIC HYDROCARBONS
CHROMATOGRAPHY
CITRATES
CRESOLS
DATA
DISULFIDES
DYES
ELECTRIC CONDUCTIVITY
ELECTRICAL PROPERTIES
EXPERIMENTAL DATA
FLUORESCENCE
GAS LASERS
HALOGEN COMPOUNDS
HALOGENATED AROMATIC HYDROCARBONS
HELIUM-NEON LASERS
HETEROCYCLIC COMPOUNDS
HYDROCARBONS
HYDROXY COMPOUNDS
INFORMATION
INTERFEROMETERS
ION EXCHANGE CHROMATOGRAPHY
LASERS
LIQUID COLUMN CHROMATOGRAPHY
LUMINESCENCE
MEASURING INSTRUMENTS
MICHELSON INTERFEROMETER
MONOCARBOXYLIC ACIDS
NITROGEN COMPOUNDS
NUMERICAL DATA
OPTICAL PROPERTIES
ORGANIC ACIDS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
ORGANIC SULFUR COMPOUNDS
OXADIAZOLES
PHENOLS
PHTHALATES
PHYSICAL PROPERTIES
POTASSIUM COMPOUNDS
REFRACTIVITY
SEPARATION PROCESSES
THIOSULFATES