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Analysis of polychlorinated biphenyls (PCBs) in human serum

Journal Article · · Environ. Health Perspect.; (United States)
DOI:https://doi.org/10.1289/ehp.8560327· OSTI ID:6337387
Polychlorinated biphenyls (PCBs) are widely dispersed in the environment. Occupational exposure to PCBs takes place, e.g., in manufacture and repair of capacitors and transformers. A special type of exposure of workers to PCBs may occur in connection with accidents where capacitors or transformers containing PCBs products are damaged, as in the case of a fire or electric arcing. The quantitation of PCBs poses several problems: there are 209 different homologs and isomers of PCBs. The isomers of PCBs have different responses in the electron capture detector, and the pattern of PCBs in biological specimens is different from that of commercial products. In this study a method was worked out for the analysis of PCBs in serum with the purpose of estimating occupation exposure to PCBs. Capillary gas chromatography with electron capture detection was used. For separation, temperature programming was used.
Research Organization:
Institute of Occupational Health, Helsinki, Finland
OSTI ID:
6337387
Journal Information:
Environ. Health Perspect.; (United States), Journal Name: Environ. Health Perspect.; (United States) Vol. 60; ISSN EVHPA
Country of Publication:
United States
Language:
English