Alpha-particle doses to human organs and tissues from internally-deposited /sup 226/Ra and /sup 228/Ra

Conference · Wed Dec 31 23:00:00 EST 1980

OSTI ID:6324501

Keane, A T; Schlenker, R A

Estimation of radiation doses to the soft tissues from internally-deposited /sup 226/Ra and /sup 228/Ra is relevant to an investigation of soft-tissue malignancies in radium-exposed persons being conducted at the Center for Human Radiobiology. Alpha-particle doses in a 50-year period following a single injection of /sup 226/Ra or /sup 228/Ra are presented for 31 soft tissues and organs of the adult human. The dose estimates were derived from the ICRP alkaline earth model fitted to data on retention of /sup 226/Ra in soft tissues and bone, combined with reported ratios of /sup 226/Ra to Ca in soft tissue and bone at natural levels and the distribution of Ca in the tissues of Reference Man (ICRP23). The median of the 31 organ and tissue doses from the ..cap alpha..-particles of /sup 226/Ra itself is 0.08 rad per injected ..mu..Ci. An additional average dose of 0.01 rad per ..mu..Ci /sup 226/Ra daughter products produced in soft tissue or transferred from bone to soft tissue. Soft-tissue doses from ..cap alpha..-particles of the /sup 228/Ra decay series are about six times those from /sup 226/Ra ..cap alpha..-particles for equal injected activities of /sup 228/Ra and /sup 226/Ra, with the assumption that /sup 228/Ra daughter products do not transfer from the organ in which they are produced. The 50-year dose to the red marrow of bone from ..cap alpha..-particles originating in bone is 0.55 rad per ..mu..Ci /sup 226/Ra injected and 1.0 rad per ..mu..Ci /sup 228/Ra injected. For ingestion by dial painters of luminous compound containg /sup 226/Ra or /sup 228/Ra with a daughter-to-parent activity ratio of 0.5, the dose to the mucosal alyer of the lower large intestine from ..cap alpha..-particles originating in the gut contents is about 0.1 rad per ..mu..Ci systemic intake of /sup 226/Ra or /sup 228/Ra.

• Research Organization: Argonne National Lab., IL (USA)
• DOE Contract Number: W-31109-ENG-38
• OSTI ID: 6324501
• Report Number(s): CONF-8110126-6; ON: DE83009022
• Country of Publication: United States
• Language: English

Related Subjects

560161* -- Radionuclide Effects
Kinetics
& Toxicology-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALINE EARTH ISOTOPES
ALPHA DECAY RADIOISOTOPES
ALPHA PARTICLES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CHARGED PARTICLES
CRITICAL ORGANS
DOSES
EVEN-EVEN NUCLEI
HEAVY NUCLEI
INTERNAL IRRADIATION
IRRADIATION
ISOTOPES
MAMMALS
MAN
NUCLEI
ORGANS
PRIMATES
RADIATION DOSES
RADIOISOTOPES
RADIUM 226
RADIUM 228
RADIUM ISOTOPES
TISSUES
VERTEBRATES
YEARS LIVING RADIOISOTOPES