Life shortening in mice exposed to fission neutrons and. gamma. rays. II. Duration-of-life and long-term fractionated exposures. [/sup 60/Co]

Journal Article · Mon Jun 01 00:00:00 EDT 1981 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3575471· OSTI ID:6318054

Thomson, J F; Williamson, F S; Grahn, D; Ainsworth, E J

Data are presented on the life shortening of B6CF/sub 1/ mice given weekly exposures to 0.85-MeV fission neutrons (0.67, 1.67, 2.67 rad per weekly fraction) or /sup 60/Co ..gamma.. rays (7, 17.4, 31.9 rad per weekly fraction) either for 60 exposures or for the duration of their lives. The life shortening produced by either the duration-of-life or the fractionated exposures was virtually identical, so the two series were treated as a single experiment. The relative biological effectiveness (RBE) for neutrons increased from 12 at 2.67 rad per weekly fraction to 21 at 0.67 rad per weekly fraction; over the dose ranges studied, the neutron RBE varied inversely with the -0.4 power of the dose. It is predicted that at 0.05 rad of neutrons per week, the RBE will approach 60 if weekly exposures to ..gamma.. radiation are chosen as the reference; if continuous ..gamma.. radiation is used as the reference, the RBE may be approximately twice as large.

• Research Organization: Argonne National Lab., IL
• DOE Contract Number: W-31-109-ENG-38
• OSTI ID: 6318054
• Journal Information: Radiat. Res.; (United States), Vol. 86:3
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
FISSION NEUTRONS
RBE
LIFE SPAN
DELAYED RADIATION EFFECTS
COBALT 60
FRACTIONATED IRRADIATION
GAMMA RADIATION
MICE
ANIMALS
BARYONS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
COBALT ISOTOPES
ELECTROMAGNETIC RADIATION
ELEMENTARY PARTICLES
FERMIONS
HADRONS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MINUTES LIVING RADIOISOTOPES
NEUTRONS
NUCLEI
NUCLEONS
ODD-ODD NUCLEI
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
RODENTS
VERTEBRATES
YEARS LIVING RADIOISOTOPES
560152* - Radiation Effects on Animals- Animals