Limiting values for the RBE of fission neutrons at low doses for life shortening in mice

Journal Article · Wed Feb 01 04:00:00 EST 1984 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3576290· OSTI ID:5126244

Storer, J B ^[1]; Mitchell, T J

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1. Oak Ridge National Lab., TN

The authors have analyzed recently published data on the effects of low doses of fission neutrons on the mean survival times of mice. The analysis for single-dose exposures was confined to doses of 20 rad or less, while for fractionated exposures only total doses of 80 rad or less were considered. They fitted the data to the frequently used power function model: life shortening = ..beta..D/sup ..gamma../, where D is the radiation dose. They show that, at low doses per fraction, either the effects are not additive or the dose-effect curve for single exposures cannot show a greater negative curvature than about the 0.9 power of dose. Analysis of the data for ..gamma.. rays showed that an exponent of 1.0 gave an acceptable fit. They conclude that at neutron doses of 20 rad or less the RBE for life shortening is constant and ranges from 13 to 22 depending on mouse strain and sex.

• DOE Contract Number: W-7405-ENG-26
• OSTI ID: 5126244
• Journal Information: Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 97:2; ISSN RAREA
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BARYONS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
DELAYED RADIATION EFFECTS
DOSE-RESPONSE RELATIONSHIPS
ELECTROMAGNETIC RADIATION
ELEMENTARY PARTICLES
FERMIONS
FISSION NEUTRONS
FRACTIONATED IRRADIATION
GAMMA RADIATION
HADRONS
IONIZING RADIATIONS
IRRADIATION
LIFE SPAN
LOW DOSE IRRADIATION
MAMMALS
MATHEMATICAL MODELS
MICE
NEUTRONS
NUCLEONS
RADIATION EFFECTS
RADIATIONS
RBE
RODENTS
VERTEBRATES