Treatment of Stages I and II cancer of the cervix: analysis of 5 year survival and recurrence rates. [Effects of surgery an incidence of complications following radiotherapy]
Eight hundred and thirty five patients with a diagnosis of Stages I or II carcinoma of the cervix were treated from 2 January 1965 to 30 June 1971. The purpose of this study was to calculate the 5 year survival rates and to analyze the treatment failures according to the modality of treatment applied. Two series of Stages Ib and IIa patients were available; one group was treated with radiotherapy, and the other with radical hysterectomy and pelvic lymphadenectomy after previous intracavitary radiumtherapy. No statistically significant difference was found in the 5 year survival of both groups. Most Stage IIb patients were treated with radiotherapy. When residual tumor was found in the uterus of a patients who underwent radical surgery after intracavitary radiumtherapy it did not influence survival. On the other hand, the presence of metastatic pelvic lymph nodes after intracavitary radium treatment was related to a lowered survival rate. The number of severe injuries was higher in patients who were treated surgically. Recurrences developed within 5 years after completion of treatment in 10.8% of Stage Ib patients, 21.5% of Stage IIa patients, and 34.5% of Stage IIb patients. Ninety per cent of these recurrences appeared within 3 years after therapy.
- Research Organization:
- Instituto Portugues de Oncologia de Francisco Gentil, Lisbon, Portugal
- OSTI ID:
- 6294255
- Journal Information:
- Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 5:3
- Country of Publication:
- United States
- Language:
- English
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62 RADIOLOGY AND NUCLEAR MEDICINE
BLADDER
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RADIOINDUCTION
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FEMALE GENITALS
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NECROSIS
NEOPLASMS
PROCTITIS
RADIOTHERAPY
SIDE EFFECTS
RECTUM
SKIN
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VOMITING
CARCINOMAS
COBALT 60
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FRACTIONATED IRRADIATION
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RADIUM
UTERUS
WOMEN
ALKALINE EARTH METALS
ANIMALS
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BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BODY
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CARDIOVASCULAR SYSTEM
COBALT ISOTOPES
DIGESTIVE SYSTEM
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DISEASES
ELECTROMAGNETIC RADIATION
ELEMENTS
FEMALES
GASTROINTESTINAL TRACT
IMPLANTS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
INTESTINES
IONIZING RADIATIONS
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MAN
MEDICINE
METALS
MINUTES LIVING RADIOISOTOPES
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
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PRIMATES
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