Technetium-99m labeled somatostatin-derived peptides for imaging

Patent · Tue Jul 06 00:00:00 EDT 1993

OSTI ID:6286964

Dean, R T; Lister-James, J; Buttram, S

A reagent is described for preparing a technetium-99m labeled peptide for imaging target sites within a mammalian body, the reagent comprising between 5 and 100 amino acid residues and at least 2 cysteine residues capable of forming a disulfide bond, wherein the reagent is directly labeled with technetium-99m by reaction with technetium-99m under reducing conditions.

• Assignee: Diatech, Inc., Londonderry, NY (United States)
• Patent Number(s): A; US 5225180
• Application Number: PPN: US 7-757470
• OSTI ID: 6286964
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AMINO ACIDS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
CARBOXYLIC ACIDS
CHEMICAL PREPARATION
DRUGS
HOURS LIVING RADIOISOTOPES
IMAGE PROCESSING
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LABELLING
MAMMALS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
PEPTIDES
PROCESSING
PROTEINS
RADIOISOTOPES
RADIOPHARMACEUTICALS
REAGENTS
SOMATOSTATIN
SYNTHESIS
TECHNETIUM 99
TECHNETIUM ISOTOPES
VERTEBRATES
YEARS LIVING RADIOI