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New rearrangement in the reaction of 1-aryl-1-(dimethylamino)-ethylenes with nitrosobenzenes. Molecular and crystal structure of N/sup 1/,N/sup 1/-dimethyl-N/sup 2/-phenyl-2-oxo(3-pyridyl)acetamidine

Journal Article · · J. Org. Chem. USSR (Engl. Transl.); (United States)
OSTI ID:6286504

The reaction of aryleneamines Ar(NMe/sub 2/)C=CH/sub 2/ (Ar = Ph, 2-Py, 3-Py, 4-Py) with nitrosobenzenes p-RC/sub 6/H/sub 4/NO (R = H, Cl, Br, Me, MeO) in benzene or ether (20/sup 0/C) is accompanied by rearrangement and leads to N/sup 1/, N/sup 1/-dimethyl-N/sup 2/-aryl-2-oxo(aryl)-acetamidines (20-40%) and a mixture of products from reduction of the nitroso compounds. The effect of temperature on the yield of the amidines is insignificant, and the presence of one or two methyl groups at the ..beta.. position of the enamine leads to the formation of only azoxybenzene. Accepting substituents in the nitrosobenzenes do not affect the yield of the rearrangement products, while donors reduce it. The reaction is accompanied by the formation of radical particles, and a reaction scheme is proposed. The acid hydrolysis of the obtained amidines and their reduction with lithium aluminum hydride were investigated.

Research Organization:
M.V. Lomonosov Moscow State Univ., USSR
OSTI ID:
6286504
Journal Information:
J. Org. Chem. USSR (Engl. Transl.); (United States), Journal Name: J. Org. Chem. USSR (Engl. Transl.); (United States) Vol. 21:9; ISSN JOCYA
Country of Publication:
United States
Language:
English

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