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Title: Radiobiological intercomparison of clinical neutron beams for growth inhibition in Vicia faba bean roots

Journal Article · · Radiat. Res.; (United States)
DOI:https://doi.org/10.2307/3577325· OSTI ID:6276329

Relative biological effectiveness (RBE) and oxygen enhancement ratio (OER) values of different neutron beams produced at the variable energy cyclotron Cyclone of Louvain-la-Neuve (Belgium) were determined. The neutrons were obtained by bombarding a beryllium target with 34-, 45-, 65-, or 75-MeV protons or with 50-MeV deuterons. The biological system was growth inhibition in Vicia faba bean roots. Taking the p(65) + Be neutron beam as a reference, RBE values were found equal to 1.36 +/- 0.2, 1.20 +/- 0.1, 1.00 (ref), 0.98 +/- 0.1, and 1.18 +/- 0.1, respectively; the doses corresponding to 50% growth inhibition were 0.39, 0.44, 0.53, 0.54, and 0.45 Gy. For the same beams, OER values were found equal to 1.55 +/- 0.1, 1.38 +/- 0.1, 1.29 +/- 0.1, 1.41 +/- 0.1, and 1.60 +/- 0.2, respectively.

Research Organization:
UCL-Cliniques Universitaires St.-Luc, Brussels (Belgium)
OSTI ID:
6276329
Journal Information:
Radiat. Res.; (United States), Vol. 117:2
Country of Publication:
United States
Language:
English